The Coagulation Cascade

coagulation cascade  Foundations · Systems · Other Languages · Secondary Hemostasis: Coagulation Cascade Watch this slide presented in a video: An The cascade consists of two pathways - the extrinsic and intrinsic pathway

Several special proteins known as coagulation factors are activated one after the other in a “cascade” effect The end result is a blood clot Coagulation is a complicated biological phenomenon which maintains the hemostasis Abnormalities in the genes that regulate the coagulation factors cause

Once coagulation is triggered by one of these pathways, clotting factors are sequentially activated in an amplification cascade, ultimately coagulation ,14,33,47 Through cross talk and feedback mechanisms, the intrinsic coagulation pathway also can be ,4,14,33,47 Both